Guitar Hero III and cases

We were thinking of getting a Guitar Hero for our Mac OS X computer that serves as entertainment computer, music, video, BZ Flag server and so on. For this project I looked around on the web to be sure to get a bundle with a guitar and compare some prices. During this process I looked at Apple's own web site and there found out, the only place I think, that Guitar Hero doesn't support case sensitive file system. Now this probably can get solved by doing a disk image with a not case sensitive file system and mounting it and installing Guitar Hero there but it got me thinking.

Not supporting case sensitive file system, WTF? It do support Mac OS X and HFS+ but not if it's formatted case sensitive. I'm not a programmer but I can only come up with one reason for not supporting case sensitive file systems, lower and upper cases are used in a way that no concern has been taken to whether they are upper or lower, why do it that way?

As I said, I'm not a programmer so if someone can enlighten me, please do. Why do some programs not support case sensitive file system?

Oh, one more thing, BZ Flag also gives you problems with case sensitive file systems but it's open source so you can follow the guidelines at the web site and change the one letter in the program that has to be changed. I'm not betting on the possibility to be able to do that with Guitar Hero.